Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.52 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127970 | 1.00 | P2RY12 (0.52) | P2RY12BMPR1BADORA1LMNASLC29A1 | |
| SCHEMBL28428736 | 0.94 | P2RY12 (0.53) | P2RY12BMPR1BADORA1LMNASLC29A1 | |
| SCHEMBL31725279 | 0.93 | LMNA (0.54) | P2RY12BMPR1BADORA1LMNASLC29A1 | |
| SCHEMBL18521420 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL21625242 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL23621389 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL314050 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL21063207 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL9294393 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA | |
| SCHEMBL314052 | 0.92 | LMNA (0.60) | ADORA1LMNASLC29A1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109451740-B | Cyclic dinucleotides for the treatment of disorders associated with STING activity, such as cancer | 先天肿瘤免疫公司 | 2022-09-02 | — | — | CN | disclosed |