Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005099 | 1.00 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005129 | 0.83 | TGFBR1 (0.71) | TGFBR1 | |
| SCHEMBL29833453 | 0.83 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005196 | 0.83 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005184 | 0.81 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL29833472 | 0.81 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005168 | 0.81 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL29833484 | 0.81 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005169 | 0.80 | TGFBR1 (0.80) | TGFBR1 | |
| SCHEMBL18005094 | 0.80 | TGFBR1 (1.00) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3259264-B1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2022-07-27 | — | — | EP | claimed |