Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NR2C2 | P49116 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29834720 | 0.99 | HRH4 (0.41) | HRH4CCR6CNR2NFKB1NR2C2 | |
| SCHEMBL24037401 | 0.88 | MAPK13 (0.47) | CNR2LRRK2MAPK13ELOVL1 | |
| SCHEMBL27096991 | 0.83 | LRRK2 (0.39) | LRRK2 | |
| SCHEMBL27096964 | 0.82 | OPRD1 (0.35) | CCR6NMT1LRRK2 | |
| SCHEMBL27096891 | 0.81 | LRRK2 (0.43) | CCR6LRRK2NR4A1 | |
| SCHEMBL11958457 | 0.81 | NR4A1 (0.37) | NR4A1 | |
| SCHEMBL29834771 | 0.80 | LRRK2 (0.43) | LRRK2 | |
| SCHEMBL29834781 | 0.80 | TYK2 (0.36) | MAPK13 | |
| SCHEMBL29834705 | 0.80 | MAP4K4 (0.43) | CCNCCDK8LRRK2 | |
| SCHEMBL11958458 | 0.80 | NR4A1 (0.36) | NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170043-A1 | QUINAZOLINE DERIVED COMPOUNDS AS EGFR INHIBITORS AND THEIR USES THEREOF | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2022-08-11 | — | — | WO | disclosed |