SCHEMBL29836414

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)C(C)C)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	IL23R	Q5VWK5	16/20	0.58

▸	TFPI	P10646	1/20	0.58

▸	F2	P00734	2/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30168754	0.97	IL23R (0.58)	IL23RTFPIF2
SCHEMBL29836399	0.96	TFPI (0.59)	IL23RTFPIF2
SCHEMBL29836338	0.95	TFPI (0.56)	IL23RTFPIF2
SCHEMBL29836514	0.95	TFPI (0.64)	IL23RTFPIF2
SCHEMBL29836540	0.94	TFPI (0.63)	IL23RTFPIF2
SCHEMBL29836412	0.94	TFPI (0.57)	IL23RTFPIF2
SCHEMBL29836469	0.94	F2 (0.56)	IL23RTFPIF2
SCHEMBL30168722	0.93	TFPI (0.59)	IL23RTFPIF2
SCHEMBL30168730	0.92	TFPI (0.56)	IL23RTFPIF2
SCHEMBL30168765	0.92	TFPI (0.63)	IL23RTFPIF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11434484-B2	Three-component CRISPR/Cas complex system and uses thereof	THE JACKSON LABORATORY (US)	2022-09-06	—	—	US	disclosed