SCHEMBL30168722

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)C(C)C)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.59

▸	F2	P00734	2/20	0.57

▸	IL23R	Q5VWK5	10/20	0.54

▸	VIPR2	P41587	3/20	0.53

▸	VIPR1	P32241	3/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29836399	0.97	TFPI (0.59)	TFPIF2IL23RVIPR2VIPR1
SCHEMBL30168765	0.96	TFPI (0.63)	TFPIF2IL23RVIPR2VIPR1
SCHEMBL30168754	0.96	IL23R (0.58)	TFPIF2IL23R
SCHEMBL30168723	0.96	TFPI (0.62)	TFPIF2IL23RVIPR2VIPR1
SCHEMBL30168689	0.96	TFPI (0.57)	TFPIF2IL23RVIPR2VIPR1
SCHEMBL29836514	0.94	TFPI (0.64)	TFPIF2IL23RVIPR1
SCHEMBL29836414	0.93	IL23R (0.58)	TFPIF2IL23R
SCHEMBL29836412	0.93	TFPI (0.57)	TFPIF2IL23RVIPR2VIPR1
SCHEMBL29836540	0.93	TFPI (0.63)	TFPIF2IL23RVIPR2VIPR1
SCHEMBL30168718	0.92	TFPI (0.61)	TFPIF2IL23RVIPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12428638-B2	Three-component CRISPR/Cas complex system and uses thereof	THE JACKSON LABORATORY (US)	2025-09-30	—	—	US	disclosed
US-20230071712-A1	THREE-COMPONENT CRISPR/CAS COMPLEX SYSTEM AND USES THEREOF	THE JACKSON LABORATORY (US)	2023-03-09	—	—	US	disclosed