Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
| ▸ | PIM1 | P11309 | 4/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 4/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.42 |
| ▸ | PRKACA | P17612 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591759 | 1.00 | DYRK1A (0.44) | DYRK1APIM1DYRK2DYRK1BAAK1 | |
| SCHEMBL29836539 | 0.87 | MET (0.44) | DYRK1APIM1DYRK2DYRK1BAAK1 | |
| SCHEMBL21591789 | 0.87 | MET (0.44) | DYRK1APIM1DYRK2DYRK1BAAK1 | |
| SCHEMBL21593178 | 0.83 | CDC7 (0.41) | DYRK1APIM1DYRK2DYRK1BAAK1 | |
| SCHEMBL29836518 | 0.83 | CDC7 (0.41) | DYRK1APIM1DYRK2DYRK1BAAK1 | |
| SCHEMBL21591777 | 0.83 | IGF1R (0.47) | DYRK1APIM1DYRK2DYRK1BJAK3 | |
| SCHEMBL29836484 | 0.83 | IGF1R (0.47) | DYRK1APIM1DYRK2DYRK1BJAK3 | |
| SCHEMBL23762196 | 0.81 | CDC7 (0.38) | DYRK1APIM1DYRK2DYRK1BAAK1 | |
| SCHEMBL21593087 | 0.79 | MET (0.41) | DYRK1APIM1CDC7ROCK2PRKACA | |
| SCHEMBL29836476 | 0.79 | MET (0.41) | DYRK1APIM1CDC7ROCK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807273-B1 | AZAINDOLE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2022-08-03 | — | — | EP | claimed |