Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23162936 | 1.00 | ESR1 (0.86) | ESR1ESR2 | |
| SCHEMBL23335863 | 1.00 | ESR1 (0.86) | ESR1ESR2 | |
| SCHEMBL19131435 | 0.92 | ESR1 (1.00) | ESR1 | |
| SCHEMBL21252997 | 0.92 | ESR1 (0.86) | ESR1ESR2 | |
| SCHEMBL29499933 | 0.92 | ESR1 (1.00) | ESR1 | |
| SCHEMBL24022037 | 0.92 | ESR1 (0.73) | ESR1 | |
| SCHEMBL23162924 | 0.92 | ESR1 (0.85) | ESR1ESR2 | |
| SCHEMBL29836589 | 0.92 | ESR1 (0.85) | ESR1ESR2 | |
| SCHEMBL29836583 | 0.92 | ESR1 (0.85) | ESR1ESR2 | |
| SCHEMBL21252979 | 0.92 | ESR1 (0.85) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545640-B2 | Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof | SANOFI (FR) | 2026-02-10 | — | — | US | disclosed |
| EP-4037768-B1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI SA (FR) | 2023-10-11 | — | — | EP | disclosed |
| US-20230115865-A1 | Novel Substituted 6,7-Dihydro-5H-Benzo[7]Annulene Compounds, Processes for Their Preparation and Therapeutic Uses Thereof | SANOFI (FR) | 2023-04-13 | — | — | US | disclosed |
| EP-4037768-A1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2022-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115865-A1 | Novel Substituted 6,7-Dihydro-5H-Benzo[7]Annulene Compounds, Processes for Their Preparation and Therapeutic Uses Thereof | ESRRA, CYP19A1, PGR | ESR1 4/4885ESR2 13/4885 |
| US-12545640-B2 | Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof | ESRRA, GPER1, FSHR | ESR1 6/4885ESR2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.