Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26693814 | 1.00 | MEN1 (0.50) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL8218007 | 0.83 | ALDH1A1 (0.51) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL30498392 | 0.78 | MEN1 (0.47) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL25757310 | 0.78 | MEN1 (0.47) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL8377843 | 0.77 | ALDH1A1 (0.68) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL17979238 | 0.77 | MEN1 (0.51) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL23796073 | 0.76 | ALDH1A1 (0.58) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL2766815 | 0.76 | MEN1 (0.58) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL38652361 | 0.76 | MEN1 (0.58) | MEN1ALDH1A1PKMKMT2ATYR | |
| SCHEMBL8222291 | 0.75 | MEN1 (0.61) | MEN1ALDH1A1PKMKMT2ATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4281182-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | Hibercell, Inc. (US) | 2023-11-29 | — | — | EP | disclosed |
| WO-2022159746-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. (US) | 2022-07-28 | — | — | WO | disclosed |