SCHEMBL29838554

SCHEMBL29838554

CCCCOC(=O)N1C[C@@H](N)C[C@H](F)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GBA2 Q9HCG7 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
MMP1 P03956 1/20 0.34
MMP3 P08254 1/20 0.34
ATM Q13315 1/20 0.34
HRH2 P25021 2/20 0.33
HRH1 P35367 2/20 0.33
DPP4 P27487 2/20 0.33
P2RY12 Q9H244 1/20 0.33
BCHE P06276 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838431 1.00 LMNA (0.46) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL3333110 0.86 LMNA (0.54) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL29838433 0.84 LMNA (0.47) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL2778567 0.81 SMN1; SMN2 (0.53) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL323088 0.81 SMN1; SMN2 (0.53) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL30816157 0.80 LMNA (0.54) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL27151384 0.80 LMNA (0.54) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL15391908 0.79 LMNA (0.48) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL22440438 0.79 SMN1; SMN2 (0.54) LMNAPOLBSMN1; SMN2GBA2ALDH1A1
SCHEMBL29838363 0.78 LMNA (0.41) LMNAPOLBSMN1; SMN2GBA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025099238-A1 COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) Universität Duisburg-Essen (DE) 2025-05-15 WO disclosed
EP-4038060-A1 DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR Pfizer Inc. (US) 2022-08-10 EP disclosed