Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 6/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845331 | 1.00 | CDK9 (0.40) | CDK9CCNT1PARP1CDC7PIM1 | |
| SCHEMBL24683415 | 1.00 | CDK9 (0.40) | CDK9CCNT1PARP1CDC7PIM1 | |
| Hydrochloric Acid SCHEMBL30769827 | 0.99 | CDK9 (0.40) | CDK9CCNT1PARP1CDC7PIM1 | |
| Hydrochloric Acid SCHEMBL27147682 | 0.99 | CDK9 (0.40) | CDK9CCNT1PARP1CDC7PIM1 | |
| Hydrochloric Acid SCHEMBL27035376 | 0.99 | CDK9 (0.40) | CDK9CCNT1PARP1CDC7PIM1 | |
| SCHEMBL30769686 | 0.95 | PARP1 (0.42) | CDK9CCNT1PARP1CDC7PIM1 | |
| SCHEMBL27035418 | 0.95 | CDK9 (0.38) | CDK9CCNT1PARP1CDC7PIM1 | |
| SCHEMBL27059762 | 0.95 | PARP1 (0.42) | CDK9CCNT1PARP1CDC7PIM1 | |
| Hydrochloric Acid SCHEMBL30769944 | 0.94 | CDK9 (0.38) | CDK9CCNT1PARP1CDC7PIM1 | |
| Hydrochloric Acid SCHEMBL30769956 | 0.94 | CDK9 (0.38) | CDK9CCNT1PARP1CDC7PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187518-A1 | SUBSTITUTED 4-PIPERIDINYL-IMIDAZO[4,5-B]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Ikena Oncology, Inc. (US) | 2022-09-09 | — | — | WO | disclosed |