Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811250 | 1.00 | SCN9A (0.33) | SCN9ATXNRD1GSRMAPTEPHX2 | |
| SCHEMBL21811211 | 0.85 | VCAM1 (0.34) | MAPTVCAM1 | |
| SCHEMBL20552538 | 0.84 | SCN9A (0.35) | SCN9A | |
| SCHEMBL24142758 | 0.83 | SCN9A (0.35) | SCN9A | |
| SCHEMBL23205965 | 0.83 | — | — | |
| SCHEMBL24997654 | 0.81 | SCN9A (0.35) | SCN9AEPHX2 | |
| SCHEMBL22681277 | 0.79 | TDP1 (0.31) | MAPTVCAM1 | |
| SCHEMBL21811248 | 0.77 | TDP1 (0.36) | MAPTVCAM1 | |
| SCHEMBL29845354 | 0.77 | TDP1 (0.36) | MAPTVCAM1 | |
| SCHEMBL30774090 | 0.77 | CCR4 (0.37) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041729-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2022-08-17 | — | — | EP | disclosed |
| EP-4038064-A1 | N-SUBSTUTUTED-6-OXO-1,6-DIHYDROPYRIMIDINE-2-YL DERIVATIVES AS INHIBITORS OF THE HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2022-08-10 | — | — | EP | disclosed |