⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535995 | 0.72 | — | — | |
| SCHEMBL503976 | 0.72 | MCL1 (0.40) | — | |
| SCHEMBL28362078 | 0.72 | KDM4E (0.67) | — | |
| SCHEMBL25197985 | 0.71 | — | — | |
| SCHEMBL18632350 | 0.69 | — | — | |
| SCHEMBL922360 | 0.69 | — | — | |
| SCHEMBL6264628 | 0.69 | — | — | |
| SCHEMBL3834024 | 0.69 | — | — | |
| SCHEMBL191971 | 0.67 | — | — | |
| SCHEMBL7999169 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10704196-B2 | Processing biomass | XYLECO, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200115723-A1 | PROCESSING BIOMASS | XYLECO, INC. | 2020-04-16 | — | — | US | disclosed |
| US-10392389-B2 | Heterocyclic compounds for the inhibition of PASK | BIOENERGENIX LLC (US) | 2019-08-27 | — | — | US | disclosed |
| WO-2019148132-A1 | GCN2 INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-08-01 | — | — | WO | disclosed |
| US-20190211501-A1 | PROCESSING BIOMASS | XYLECO, INC. | 2019-07-11 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| EP-2721033-B1 | COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR USES AS IDH1 MUTANTS INHIBITORS FOR TREATING CANCERS | AGIOS PHARMACEUTICALS INC (US) | 2016-12-07 | — | — | EP | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| EP-2029543-B1 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH LLC (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014062733-A2 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2014-04-24 | — | — | WO | disclosed |
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | disclosed |
| EP-2029543-A2 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-2027093-A2 | SUBSTITUTED CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007146376-A2 | SUBSTITUTED 3-CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007146323-A2 | SUBSTITUTED CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC | 2007-12-13 | — | — | US | disclosed |
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
| US-4897467-A | ELECTRON DONOR-ACCEPTOR ADSORPTION; HYDROPHILIC POLYMER NETWORK WITH LIGANDS CONTAINING NITRILE GROUPS | GELINNOVATION H.B. (SE) | 1990-01-30 | — | — | US | disclosed |