SCHEMBL503976

SCHEMBL503976

C=C(CC#N)C(=C)CC#N

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.40
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50985 0.78
SCHEMBL10535995 0.77
SCHEMBL25197985 0.76
SCHEMBL18632350 0.74
SCHEMBL6264628 0.74
SCHEMBL2984565 0.72
SCHEMBL8905834 0.72
SCHEMBL1996348 0.72
SCHEMBL17230385 0.72
SCHEMBL7999169 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060189774-A1 Modifiable polyunsaturated polymers and processes for their preparation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH 2006-08-24 US claimed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US claimed
US-12378327-B2 Method of making a silica/cellulose hybrid THE GOODYEAR TIRE & RUBBER COMPANY (US) 2025-08-05 US disclosed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
US-11912798-B2 Rubber with backbone and end-group functionalization THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-02-27 US disclosed
CN-114621375-A Rubber with main chain and end group functionalization 固特异轮胎和橡胶公司 2022-06-14 CN disclosed
US-20220177610-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2022-06-09 US disclosed
CN-114591518-A Process for preparing silica/cellulose mixtures 固特异轮胎和橡胶公司 2022-06-07 CN disclosed
US-20220169752-A1 METHOD OF MAKING A SILICA/CELLULOSE HYBRID THE GOODYEAR TIRE & RUBBER COMPANY 2022-06-02 US disclosed
US-9587060-B2 Functionalized rubbery polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-03-07 US disclosed
US-9550839-B2 Copolymers of conjugated triene monomers for improved filler interaction THE GOODYEAR TIRE & RUBBER COMPANY (US) 2017-01-24 US disclosed
US-6627722-B2 Rubber comprising comonomers of conjugated diolefin and vinyllaromatic compound substituted with N-heterocycle; tire treads GOODYEAR TIRE & RUBBER COMPANY, THE 2003-09-30 US disclosed
US-6627721-B1 Rubbery polymer comprised of comonomers of conjugated diene and styrene substited with N-heterocycle or sulfide; hoses, power transmission belts THE GOODYEAR TIRE & RUBBER COMPANY 2003-09-30 US disclosed
US-20030134997-A1 Functionalized elastomers THE GOODYEAR TIRE & RUBBER COMPANY 2003-07-17 US disclosed
US-6583260-B2 Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-06-24 US disclosed
US-6583260-B2 Such as 2-(N,N-dimethylaminomethyl)-1,3- butadiene); for use in adhesives, sealants, surfactants, elastomers, ionomers, coatings and membranes IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2003-06-24 US disclosed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US disclosed
US-20020151673-A1 Functionalized diene monomers and polymers containing functionalized dienes and methods for their preparation SHEARES VALERIE V (US) 2002-10-17 US disclosed
US-6344538-B1 REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2002-02-05 US disclosed
US-6344538-B1 REACTION OF 3-BROMOMETHYL-2,5-HYDROTHIOPHENE-1,1-DIOXIDE WITH NUCLEOPHILE WITH AMINE, HYDROXY, CARBOXY ACID, ESTER OR NITRILE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2002-02-05 US disclosed