Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29846629 | 0.88 | NPSR1 (0.39) | SMN1; SMN2ALDH1A1GAACARM1MAPT | |
| SCHEMBL29846504 | 0.86 | HDAC6 (0.40) | DHODHELANE | |
| SCHEMBL29846438 | 0.86 | KLKB1 (0.39) | DHODHHPGDLMNA | |
| SCHEMBL29847129 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL29846561 | 0.80 | MAPT (0.41) | SMN1; SMN2ALDH1A1DHODHCARM1MAPT | |
| SCHEMBL29846627 | 0.80 | MAPT (0.57) | SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL29846815 | 0.80 | KMT2A (0.39) | SMN1; SMN2ALDH1A1GAADHODHELANE | |
| SCHEMBL29846956 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1GAADHODHBRD4 | |
| SCHEMBL29846771 | 0.79 | PHGDH (0.42) | SMN1; SMN2DHODH | |
| SCHEMBL29846399 | 0.76 | MAPT (0.62) | SMN1; SMN2ALDH1A1DHODHMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123530-A1 | BORONIC ACID COMPOUND | 주식회사 엘지화학 | 2022-06-16 | — | — | WO | disclosed |