Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548454 | 0.82 | SLC6A2 (0.48) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL16422767 | 0.82 | KDM1A (0.46) | KDM1AMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16422768 | 0.82 | KDM1A (0.46) | KDM1AMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16422783 | 0.82 | KDM1A (0.46) | KDM1AMAOBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12926851 | 0.81 | TSHR (0.48) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL14589045 | 0.81 | TSHR (0.48) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1265896 | 0.81 | TSHR (0.48) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1265897 | 0.81 | TSHR (0.48) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL1265899 | 0.81 | TSHR (0.48) | KDM1AMAOBKCNH2RCOR1KDM1B | |
| SCHEMBL6073182 | 0.80 | SLC6A2 (0.41) | KDM1AMAOBKCNH2RCOR1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115038700-A | Gem disubstituted heterocyclic compounds and their use as IDH inhibitors | 内尔维亚诺医疗科学公司 | 2022-09-09 | — | — | CN | disclosed |