Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 5/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.51 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ERBB3 | P21860 | 3/20 | 0.47 |
| ▸ | STAT6 | P42226 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCND1 | P24385 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513629 | 1.00 | JUN (0.51) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL16515090 | 0.94 | JUN (0.51) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL29848062 | 0.92 | MAPK10 (0.45) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL16513785 | 0.92 | MAPK10 (0.45) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL16514545 | 0.91 | CDK4 (0.46) | JUNMAPK8MAPK10EGFRERBB3 | |
| SCHEMBL29847455 | 0.91 | CDK4 (0.46) | JUNMAPK8MAPK10EGFRERBB3 | |
| SCHEMBL16515297 | 0.90 | JUN (0.49) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL29848104 | 0.89 | JUN (0.51) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL16823199 | 0.89 | JUN (0.51) | JUNMAPK8MAPK10SYKTTK | |
| SCHEMBL16515095 | 0.88 | SYK (0.46) | JUNMAPK8MAPK10SYKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |