Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.85 |
| ▸ | BTK | Q06187 | 12/20 | 0.67 |
| ▸ | ITK | Q08881 | 4/20 | 0.67 |
| ▸ | JAK2 | O60674 | 1/20 | 0.67 |
| ▸ | LYN | P07948 | 1/20 | 0.67 |
| ▸ | TEC | P42680 | 1/20 | 0.67 |
| ▸ | TXK | P42681 | 1/20 | 0.67 |
| ▸ | BMX | P51813 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | CD69 | Q07108 | 1/20 | 0.67 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514391 | 1.00 | EGFR (0.85) | EGFRBTKITKJAK2LYN | |
| SCHEMBL29847612 | 0.92 | EGFR (1.00) | EGFRBTKITKJAK2LYN | |
| SCHEMBL16514281 | 0.92 | EGFR (1.00) | EGFRBTKITKJAK2LYN | |
| SCHEMBL21156030 | 0.90 | EGFR (0.80) | EGFRBTKITKJAK3FGFR2 | |
| SCHEMBL16514613 | 0.90 | EGFR (0.83) | EGFRBTKITKJAK2LYN | |
| SCHEMBL29848073 | 0.90 | EGFR (0.83) | EGFRBTKITKJAK2LYN | |
| SCHEMBL15987165 | 0.87 | EGFR (0.65) | EGFRBTKITKJAK2LYN | |
| SCHEMBL16514035 | 0.86 | EGFR (0.79) | EGFRBTKJAK3FGFR2 | |
| SCHEMBL29847049 | 0.86 | EGFR (0.79) | EGFRBTKJAK3FGFR2 | |
| SCHEMBL20807715 | 0.85 | EGFR (0.77) | EGFRBTKITKJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |