Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.40 |
| ▸ | CCND1 | P24385 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CCND2 | P30279 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513501 | 1.00 | CDK4 (0.40) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL16514406 | 0.94 | PLK1 (0.41) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL29848213 | 0.94 | PLK1 (0.41) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL29848062 | 0.91 | MAPK10 (0.45) | CDK4CCND1CSF1RSYKFGFR1 | |
| SCHEMBL16513785 | 0.91 | MAPK10 (0.45) | CDK4CCND1CSF1RSYKFGFR1 | |
| SCHEMBL16514545 | 0.91 | CDK4 (0.46) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL29847455 | 0.91 | CDK4 (0.46) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL16514101 | 0.89 | MYLK4 (0.43) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL29847686 | 0.89 | MYLK4 (0.43) | CDK4CCND1CDK1CCNB1CCNE1 | |
| SCHEMBL16514857 | 0.88 | ACVR1 (0.42) | CDK4CCND1MYLK4CLK4STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |