Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 7/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 5/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 4/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514101 | 1.00 | MYLK4 (0.43) | MYLK4CLK4STK17ATBK1CDK4 | |
| SCHEMBL16514253 | 0.94 | MYLK4 (0.41) | MYLK4CLK4STK17ATBK1CDK4 | |
| SCHEMBL29847075 | 0.94 | MYLK4 (0.41) | MYLK4CLK4STK17ATBK1CDK4 | |
| SCHEMBL29847797 | 0.91 | BRAF (0.41) | CDK4CDK6CSF1RCDK2ZAP70 | |
| SCHEMBL16514429 | 0.91 | BRAF (0.41) | CDK4CDK6CSF1RCDK2ZAP70 | |
| SCHEMBL29848066 | 0.91 | CDK2 (0.46) | MYLK4STK17ACDK4ACVR1CCND1 | |
| SCHEMBL16514184 | 0.91 | CDK2 (0.46) | MYLK4STK17ACDK4ACVR1CCND1 | |
| SCHEMBL16513501 | 0.89 | CDK4 (0.40) | MYLK4CLK4STK17ATBK1CDK4 | |
| SCHEMBL29847710 | 0.89 | CDK4 (0.40) | MYLK4CLK4STK17ATBK1CDK4 | |
| SCHEMBL16515263 | 0.88 | MYLK4 (0.45) | MYLK4CLK4STK17ATBK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |