Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.45 |
| ▸ | CCND1 | P24385 | 2/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823173 | 1.00 | SRC (0.47) | SRCJAK2PLK4SYKEGFR | |
| SCHEMBL29847814 | 0.94 | MYLK4 (0.46) | SRCJAK2SYKEGFRJUN | |
| SCHEMBL16822855 | 0.94 | MYLK4 (0.46) | SRCJAK2SYKEGFRJUN | |
| SCHEMBL29848034 | 0.92 | SRC (0.49) | SRCJAK2SYKEGFRPIK3CA | |
| SCHEMBL16515228 | 0.91 | AIMP2 (0.48) | SRCSYKEGFRPIK3CACDK2 | |
| SCHEMBL29847941 | 0.91 | AIMP2 (0.48) | SRCSYKEGFRPIK3CACDK2 | |
| SCHEMBL16823034 | 0.90 | CDK1 (0.54) | SRCJAK2PLK4EGFRCDK2 | |
| SCHEMBL29847977 | 0.90 | CDK1 (0.54) | SRCJAK2PLK4EGFRCDK2 | |
| SCHEMBL29847788 | 0.89 | SYK (0.46) | JAK2PLK4SYKJUNMAPK8 | |
| SCHEMBL29847808 | 0.89 | SRC (0.49) | SRCSYKEGFRPIK3CACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |