Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16515228 | 1.00 | AIMP2 (0.48) | AIMP2SRCSYKEGFRBTK | |
| SCHEMBL16513648 | 0.95 | SRC (0.44) | AIMP2SRCSYKEGFRBTK | |
| SCHEMBL29847519 | 0.95 | SRC (0.44) | AIMP2SRCSYKEGFRBTK | |
| SCHEMBL16823173 | 0.91 | SRC (0.47) | SRCSYKEGFRBTKPIK3CA | |
| SCHEMBL29847732 | 0.91 | SRC (0.47) | SRCSYKEGFRBTKPIK3CA | |
| SCHEMBL29847867 | 0.90 | CDK1 (0.50) | AIMP2SRCEGFRBRAFBACE1 | |
| SCHEMBL16514778 | 0.90 | CDK1 (0.50) | AIMP2SRCEGFRBRAFBACE1 | |
| SCHEMBL29847808 | 0.90 | SRC (0.49) | AIMP2SRCSYKEGFRBTK | |
| SCHEMBL16515089 | 0.89 | BRAF (0.44) | AIMP2SRCSYKEGFRBTK | |
| SCHEMBL29847932 | 0.89 | BRAF (0.44) | AIMP2SRCSYKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |