Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.43 |
| ▸ | MYLK4 | Q86YV6 | 2/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513754 | 1.00 | KDR (0.47) | KDRCDK1CCNA2CDK2TTK | |
| SCHEMBL29847867 | 0.94 | CDK1 (0.50) | KDRCDK1CCNA2CDK2TTK | |
| SCHEMBL16514778 | 0.94 | CDK1 (0.50) | KDRCDK1CCNA2CDK2TTK | |
| SCHEMBL16822948 | 0.92 | MYLK4 (0.41) | KDRCDK1CCNA2CDK2TTK | |
| SCHEMBL29848140 | 0.91 | CDK1 (0.51) | KDRCDK1CCNA2CDK2TTK | |
| SCHEMBL16823076 | 0.91 | CDK1 (0.51) | KDRCDK1CCNA2CDK2TTK | |
| SCHEMBL16513648 | 0.91 | SRC (0.44) | TBK1MYLK4STK17ACLK4BACE1 | |
| SCHEMBL29847519 | 0.91 | SRC (0.44) | TBK1MYLK4STK17ACLK4BACE1 | |
| SCHEMBL16823227 | 0.89 | SYK (0.44) | KDRCDK1TBK1MYLK4STK17A | |
| SCHEMBL29847414 | 0.88 | PIK3CD (0.43) | KDRCDK1TBK1MYLK4STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |