Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 3/20 | 0.44 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.41 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513648 | 1.00 | SRC (0.44) | SRCSYKAIMP2EGFRBTK | |
| SCHEMBL16515228 | 0.95 | AIMP2 (0.48) | SRCSYKAIMP2EGFRBTK | |
| SCHEMBL29847941 | 0.95 | AIMP2 (0.48) | SRCSYKAIMP2EGFRBTK | |
| SCHEMBL29847814 | 0.92 | MYLK4 (0.46) | SRCSYKEGFRBTKPRKCQ | |
| SCHEMBL16822855 | 0.92 | MYLK4 (0.46) | SRCSYKEGFRBTKPRKCQ | |
| SCHEMBL29847765 | 0.91 | KDR (0.47) | SRCEGFRPRKCQACVR1MYLK4 | |
| SCHEMBL16513754 | 0.91 | KDR (0.47) | SRCEGFRPRKCQACVR1MYLK4 | |
| SCHEMBL16823227 | 0.90 | SYK (0.44) | SRCSYKAIMP2EGFRBTK | |
| SCHEMBL16515150 | 0.90 | PRKCQ (0.46) | SRCSYKAIMP2EGFRBTK | |
| SCHEMBL29848176 | 0.90 | PRKCQ (0.46) | SRCSYKAIMP2EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |