Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822880 | 0.89 | SYK (0.45) | SYKSRCCDK1KDREGFR | |
| SCHEMBL29847550 | 0.89 | SYK (0.45) | SYKSRCCDK1KDREGFR | |
| SCHEMBL29847808 | 0.89 | SRC (0.49) | SYKSRCCDK1KDREGFR | |
| SCHEMBL16823227 | 0.86 | SYK (0.44) | SYKSRCCDK1KDREGFR | |
| SCHEMBL16515102 | 0.83 | SYK (0.43) | SYKSRCCDK1KDREGFR | |
| SCHEMBL16823021 | 0.80 | BACE1 (0.45) | SYKSRCCDK1KDREGFR | |
| SCHEMBL29846933 | 0.80 | BACE1 (0.45) | SYKSRCCDK1KDREGFR | |
| SCHEMBL29848034 | 0.80 | SRC (0.49) | SYKSRCCDK1KDREGFR | |
| SCHEMBL29847543 | 0.78 | BACE1 (0.48) | SYKSRCCDK1KDREGFR | |
| SCHEMBL16515429 | 0.78 | BACE1 (0.48) | SYKSRCCDK1KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |