Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822880 | 1.00 | SYK (0.45) | SYKBACE1AIMP2SRCZAP70 | |
| SCHEMBL16823227 | 0.95 | SYK (0.44) | SYKBACE1AIMP2SRCZAP70 | |
| SCHEMBL29846933 | 0.91 | BACE1 (0.45) | SYKBACE1AIMP2SRCZAP70 | |
| SCHEMBL16823021 | 0.91 | BACE1 (0.45) | SYKBACE1AIMP2SRCZAP70 | |
| SCHEMBL29847820 | 0.89 | SYK (0.46) | SYKBACE1SRCEGFRBTK | |
| SCHEMBL16515228 | 0.89 | AIMP2 (0.48) | SYKBACE1AIMP2SRCEGFR | |
| SCHEMBL16823103 | 0.89 | ZAP70 (0.42) | SRCZAP70EGFRBTKCDK1 | |
| SCHEMBL29847941 | 0.89 | AIMP2 (0.48) | SYKBACE1AIMP2SRCEGFR | |
| SCHEMBL29847827 | 0.89 | AIMP2 (0.46) | SYKBACE1AIMP2SRCZAP70 | |
| SCHEMBL16823092 | 0.89 | AIMP2 (0.46) | SYKBACE1AIMP2SRCZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |