Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.66 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.65 |
| ▸ | JAK3 | P52333 | 5/20 | 0.61 |
| ▸ | JAK2 | O60674 | 4/20 | 0.61 |
| ▸ | JAK1 | P23458 | 4/20 | 0.61 |
| ▸ | TYK2 | P29597 | 2/20 | 0.61 |
| ▸ | BTK | Q06187 | 4/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | TTK | P33981 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 2/20 | 0.54 |
| ▸ | BLK | P51451 | 2/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513680 | 1.00 | EGFR (0.66) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL16514873 | 0.91 | EGFR (0.61) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL16514536 | 0.91 | EGFR (0.70) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL16514927 | 0.91 | EGFR (0.65) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL16513980 | 0.90 | EGFR (0.81) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL29847865 | 0.90 | EGFR (0.81) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL16515112 | 0.90 | EGFR (0.83) | EGFRFGFR2JAK3JAK2BTK | |
| SCHEMBL16514018 | 0.88 | FGFR2 (0.83) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL16513694 | 0.88 | EGFR (0.69) | EGFRFGFR2JAK3JAK2JAK1 | |
| SCHEMBL29847929 | 0.88 | EGFR (0.69) | EGFRFGFR2JAK3JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |