Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 3/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16513790 | 1.00 | WEE1 (0.43) | WEE1EGFRCDK4PIK3CDCSF1R | |
| SCHEMBL29847956 | 0.90 | EGFR (0.53) | WEE1EGFRCDK4CDK1CCNB1 | |
| SCHEMBL16513782 | 0.90 | EGFR (0.53) | WEE1EGFRCDK4CDK1CCNB1 | |
| SCHEMBL29847776 | 0.88 | EGFR (0.55) | WEE1EGFRSRCMAP3K5FGFR1 | |
| SCHEMBL16513658 | 0.88 | EGFR (0.55) | WEE1EGFRSRCMAP3K5FGFR1 | |
| SCHEMBL16823058 | 0.88 | KCNH2 (0.44) | WEE1EGFRCDK4PIK3CDCSF1R | |
| SCHEMBL16514431 | 0.87 | WEE1 (0.51) | WEE1CDK4PIK3CDCSF1RCDK6 | |
| SCHEMBL29847871 | 0.87 | WEE1 (0.51) | WEE1CDK4PIK3CDCSF1RCDK6 | |
| SCHEMBL16513756 | 0.87 | WEE1 (0.45) | WEE1EGFRCDK4CDK6CDK1 | |
| SCHEMBL16513836 | 0.85 | WEE1 (0.48) | WEE1CDK4PIK3CDCSF1RCDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |