Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 5/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.40 |
| ▸ | WEE1 | P30291 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514888 | 1.00 | SYK (0.47) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL16822982 | 0.95 | SYK (0.49) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL29847780 | 0.95 | SYK (0.49) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL16514147 | 0.94 | SYK (0.47) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL29847785 | 0.94 | SYK (0.47) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL29848065 | 0.92 | JUN (0.48) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL16514508 | 0.92 | JUN (0.48) | SYKEGFRBTKJUNMAPK8 | |
| SCHEMBL16514910 | 0.89 | BACE1 (0.43) | SYKEGFRBTKBACE1AXL | |
| SCHEMBL29848464 | 0.89 | SYK (0.43) | SYKEGFRBTKBACE1AXL | |
| SCHEMBL16515383 | 0.89 | SYK (0.43) | SYKEGFRBTKBACE1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |