Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 5/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.62 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 5/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.55 |
| ▸ | TTK | P33981 | 1/20 | 0.55 |
| ▸ | PLK4 | O00444 | 2/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.53 |
| ▸ | CDK2 | P24941 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | CDK4 | P11802 | 2/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.53 |
| ▸ | CCND1 | P24385 | 2/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16514379 | 1.00 | JUN (0.62) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL16513981 | 0.92 | SYK (0.60) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL16513535 | 0.90 | SYK (0.56) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL29847981 | 0.90 | SYK (0.58) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL16514074 | 0.90 | SYK (0.58) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL16515124 | 0.89 | MAPK10 (0.52) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL29848435 | 0.89 | MAPK10 (0.52) | JUNMAPK8MAPK10SYKSTAT6 | |
| SCHEMBL16514148 | 0.88 | WEE1 (0.55) | JUNMAPK8MAPK10STAT6CCNE1 | |
| SCHEMBL29847505 | 0.88 | WEE1 (0.55) | JUNMAPK8MAPK10STAT6CCNE1 | |
| SCHEMBL16513491 | 0.88 | SYK (0.58) | JUNMAPK8MAPK10SYKSTAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |