Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.46 |
| ▸ | JUN | P05412 | 4/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 3/20 | 0.45 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16515150 | 1.00 | PRKCQ (0.46) | PRKCQMAPK10JUNMAPK8SRC | |
| SCHEMBL16514308 | 0.95 | AIMP2 (0.49) | PRKCQMAPK10JUNMAPK8SRC | |
| SCHEMBL16514604 | 0.92 | MAPK10 (0.47) | MAPK10JUNMAPK8SRCSYK | |
| SCHEMBL29847900 | 0.92 | MAPK10 (0.47) | MAPK10JUNMAPK8SRCSYK | |
| SCHEMBL16513536 | 0.92 | MAPK10 (0.53) | PRKCQMAPK10JUNMAPK8SRC | |
| SCHEMBL29847682 | 0.92 | MAPK10 (0.53) | PRKCQMAPK10JUNMAPK8SRC | |
| SCHEMBL29847519 | 0.90 | SRC (0.44) | PRKCQSRCSYKAIMP2EGFR | |
| SCHEMBL29847446 | 0.90 | SYK (0.43) | MAPK10JUNMAPK8SRCSYK | |
| SCHEMBL16513648 | 0.90 | SRC (0.44) | PRKCQSRCSYKAIMP2EGFR | |
| SCHEMBL16513803 | 0.90 | SYK (0.43) | MAPK10JUNMAPK8SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-B | Chemical entities, compositions, and methods | 润新生物公司 | 2022-08-16 | — | — | CN | disclosed |