Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL3 | P20749 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431762 | 1.00 | BCL3 (1.00) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL17554128 | 0.93 | BCL3 (1.00) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL16431436 | 0.92 | BCL3 (1.00) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL8161181 | 0.92 | BCL3 (0.84) | BCL3KMT2AALDH1A1 | |
| SCHEMBL17554146 | 0.91 | BCL3 (0.84) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL17870595 | 0.91 | BCL3 (1.00) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL17554022 | 0.91 | BCL3 (0.85) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL16430979 | 0.90 | BCL3 (0.81) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL19348406 | 0.87 | BCL3 (0.78) | BCL3KMT2AALDH1A1HTTGAA | |
| SCHEMBL30560633 | 0.87 | BCL3 (0.78) | BCL3KMT2AALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027594-B1 | 2-BENZOYLAMINOBENZAMIDE DERIVATIVES AS BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2022-08-10 | — | — | EP | claimed |
| EP-3027594-B1 | 2-BENZOYLAMINOBENZAMIDE DERIVATIVES AS BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2022-08-10 | — | — | EP | disclosed |