SCHEMBL30560633

SCHEMBL30560633

CN1CCN(CCNC(=O)c2ccccc2NC(=O)c2ccccc2F)CC1

nearest known ligand 0.78

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BCL3 P20749 8/20 0.78
▸ KMT2A Q03164 2/20 0.57
▸ POLB P06746 2/20 0.54
▸ TSHR P16473 1/20 0.54
▸ ALDH1A1 P00352 2/20 0.53
▸ GAA P10253 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ HCN1 O60741 1/20 0.52
▸ MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19348406 1.00 BCL3 (0.78) BCL3KMT2APOLBTSHRALDH1A1
SCHEMBL17554040 0.93 BCL3 (0.78) BCL3KMT2APOLBALDH1A1HCN1
SCHEMBL30560619 0.93 BCL3 (0.78) BCL3KMT2APOLBALDH1A1HCN1
SCHEMBL19348412 0.92 BCL3 (0.78) BCL3KMT2APOLBTSHRALDH1A1
SCHEMBL30560635 0.92 BCL3 (0.78) BCL3KMT2APOLBTSHRALDH1A1
SCHEMBL19348436 0.90 BCL3 (0.80) BCL3KMT2APOLBTSHRALDH1A1
SCHEMBL30560485 0.90 BCL3 (0.80) BCL3KMT2APOLBTSHRALDH1A1
SCHEMBL29849775 0.87 BCL3 (1.00) BCL3KMT2APOLBALDH1A1GAA
SCHEMBL16431762 0.87 BCL3 (1.00) BCL3KMT2APOLBALDH1A1GAA
SCHEMBL17554147 0.87 BCL3 (0.63) BCL3KMT2AALDH1A1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3628374-B1 BCL-3 INHIBITORS UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) 2023-08-30 — — EP disclosed
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