Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 8/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28955143 | 1.00 | SNCA (0.48) | SNCANOX1GAAMAPTMEN1 | |
| Iodide SCHEMBL1206518 | 1.00 | SNCA (0.48) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL64975 | 0.98 | SNCA (0.50) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL29625245 | 0.98 | SNCA (0.50) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL29600380 | 0.98 | SNCA (0.50) | SNCANOX1GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL12470954 | 0.95 | SNCA (0.48) | SNCANOX1GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL31175976 | 0.95 | SNCA (0.48) | SNCANOX1GAAMAPTMEN1 | |
| Iodide SCHEMBL12813169 | 0.90 | NOX1 (0.63) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL28571001 | 0.90 | NOX1 (0.48) | SNCANOX1GAAMAPTMEN1 | |
| SCHEMBL30867071 | 0.90 | NOX1 (0.48) | SNCANOX1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104606199-B | 3, 7-diamino-10H-phenothiazine compound salt and use thereof | 维斯塔实验室有限公司 | 2022-09-13 | — | — | CN | disclosed |