SCHEMBL64975

SCHEMBL64975

Nc1ccc2c(c1)Sc1cc(N)ccc1N2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 8/20 0.50
NOX1 Q9Y5S8 9/20 0.47
GAA P10253 5/20 0.46
MAPT P10636 5/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
TDP1 Q9NUW8 3/20 0.46
SLC6A2 P23975 2/20 0.46
HTR2C P28335 2/20 0.46
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
MAOA P21397 1/20 0.46
CNR1 P21554 1/20 0.46
PTGS1 P23219 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29600380 1.00 SNCA (0.50) SNCANOX1GAAMAPTMEN1
SCHEMBL29625245 1.00 SNCA (0.50) SNCANOX1GAAMAPTMEN1
Hydrochloric Acid SCHEMBL12470954 0.98 SNCA (0.48) SNCANOX1GAAMAPTMEN1
Hydrochloric Acid SCHEMBL31175976 0.98 SNCA (0.48) SNCANOX1GAAMAPTMEN1
Iodide SCHEMBL1206518 0.98 SNCA (0.48) SNCANOX1GAAMAPTMEN1
Iodide SCHEMBL29850697 0.98 SNCA (0.48) SNCANOX1GAAMAPTMEN1
Iodide SCHEMBL28955143 0.98 SNCA (0.48) SNCANOX1GAAMAPTMEN1
SCHEMBL28571001 0.92 NOX1 (0.48) SNCANOX1GAAMAPTMEN1
SCHEMBL30867071 0.92 NOX1 (0.48) SNCANOX1GAAMAPTMEN1
SCHEMBL237910 0.90 NOX1 (0.65) SNCANOX1GAAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 543 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188379-A1 FUSED-RING POLYCYCLIC AMINE FUNCTIONALIZED OLEFINIC POLYMERS FOR LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-12 US claimed
US-20190151329-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (SG) 2019-05-23 US claimed
US-10188658-B2 Therapeutic use of diaminophenothiazines WISTA LABORATORIES LTD. (SG) 2019-01-29 US claimed
EP-2954932-B1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LAB LTD (SG) 2018-09-19 EP claimed
US-20170050044-A1 Integumentary System Therapy LEBOVITZ RUSSELL M (US) 2017-02-23 US claimed
EP-2978856-B1 SELECTIVE CHROMOGENIC MEDIUM Szegedi Tudományegyetem (HU) 2017-02-22 EP claimed
WO-2017015174-A1 INTEGUMENTARY SYSTEM THERAPY LEBOVITZ RUSSELL M (US) 2017-01-26 WO claimed
CN-106353307-A Small-size color change indication device 深圳九星印刷包装集团有限公司 2017-01-25 CN claimed
US-20160237048-A1 PHENOTHIAZINE DIAMINIUM SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2016-08-18 US claimed
US-20160051559-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE WISTA LABORATORIES LTD. (SG) 2016-02-25 US claimed
US-20100280975-A1 SYSTEMS FOR CLINICAL TRIALS WISTA LABORATORIES LTD. 2010-11-04 US claimed
EP-2227766-A2 SYSTEMS FOR CLINICAL TRIALS Wista Laboratories Ltd. (SG) 2010-09-15 EP claimed
EP-2205245-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES Wista Laboratories Ltd. (SG) 2010-07-14 EP claimed
WO-2009060191-A2 SYSTEMS FOR CLINICAL TRIALS WISTA LABORATORIES LTD. (GB) 2009-05-14 WO claimed
WO-2009044127-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES WISTA LABORATORIES LTD. (GB) 2009-04-09 WO claimed
WO-2009007376-A1 PHARMACEUTICAL COMPOSITIONS FOR PERORAL ADMINISTRATION OF PHENOTHIAZINE DYESTUFFS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2009-01-15 WO claimed
WO-2007144048-A2 PRESENTATION FORM FOR THE ORAL ADMINISTRATION OF PHENOTHIAZINE DYES, ITS PRODUCTION AND USE DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) 2007-12-21 WO claimed
CN-101022852-A Acousto-optic dynamic therapy for dental applications ONDINE INT LTD (BB) 2007-08-22 CN claimed
US-5486582-A Polymer scale preventive process using a coating of chitosan salt and phenothiazine SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-01-23 US claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170050044-A1 Integumentary System Therapy OTC, SUCLG1, TYR SNCA 3988/4885NOX1 428/4885GAA 340/4885
US-20160051559-A1 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE PSEN1, PSEN2, APP SNCA 673/4885NOX1 187/4885GAA 2333/4885
US-20160237048-A1 PHENOTHIAZINE DIAMINIUM SALTS AND THEIR USE QDPR, SLC35A1, SLC6A7 SNCA 427/4885NOX1 2683/4885GAA 102/4885
US-10188658-B2 Therapeutic use of diaminophenothiazines QDPR, DDO, HNMT SNCA 430/4885NOX1 2397/4885GAA 228/4885
US-20190151329-A1 THERAPEUTIC USE OF DIAMINOPHENOTHIAZINES QDPR, DDO, HNMT SNCA 398/4885NOX1 2264/4885GAA 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.