Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 11/20 | 0.45 |
| ▸ | NPY1R | P25929 | 6/20 | 0.45 |
| ▸ | NPY2R | P49146 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30122969 | 0.91 | NPY4R (0.44) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL29679761 | 0.91 | BACE1 (0.47) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL29784994 | 0.91 | NPY4R (0.45) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL8526711 | 0.91 | NPY4R (0.44) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL27086265 | 0.91 | NPY4R (0.44) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL27086281 | 0.91 | NPY4R (0.44) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL8526706 | 0.91 | NPY4R (0.44) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL29816322 | 0.90 | NPY4R (0.46) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL30350463 | 0.89 | PDCD1LG2 (0.43) | PDCD1LG2CD274NPY4RNPY1RNPY2R | |
| SCHEMBL31410856 | 0.89 | BACE1 (0.47) | NPY4RNPY1RNPY2RNPY5RCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11628202-B2 | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia | NYMOX CORPORATION (CA) | 2023-04-18 | — | — | US | disclosed |
| CN-115044652-A | Nucleic acid detection kit based on CRISPR/Cas12a system and up-conversion luminescent particle immunochromatography and application | 中国人民解放军军事科学院军事医学研究院 | 2022-09-13 | — | — | CN | disclosed |
| WO-2022035799-A1 | HETEROCYCLE CDK INHIBITORS AND THEIR USE THEREOF | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-02-17 | — | — | WO | disclosed |