SCHEMBL30122969

SCHEMBL30122969

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nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.44
NPY1R P25929 6/20 0.44
NPY2R P49146 4/20 0.44
NPY5R Q15761 4/20 0.44
KEAP1 Q14145 1/20 0.41
ENPEP Q07075 5/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
CTSD P07339 1/20 0.40
BACE1 P56817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30350463 0.94 PDCD1LG2 (0.43) NPY4RNPY1RNPY2RNPY5RKEAP1
SCHEMBL31393361 0.94 ENPEP (0.44) NPY4RNPY1RNPY2RNPY5RENPEP
SCHEMBL29850992 0.91 PDCD1LG2 (0.49) NPY4RNPY1RNPY2RNPY5RPDCD1LG2
SCHEMBL29679761 0.91 BACE1 (0.47) NPY4RNPY1RNPY2RNPY5RPDCD1LG2
SCHEMBL7306013 0.90 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RENPEP
SCHEMBL30797917 0.90 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RENPEP
SCHEMBL8526711 0.89 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RPDCD1LG2
SCHEMBL8526706 0.89 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RPDCD1LG2
SCHEMBL27086265 0.89 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RPDCD1LG2
SCHEMBL27086281 0.89 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RPDCD1LG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 WO disclosed