Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 11/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539459 | 1.00 | UBE2M (0.41) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL25732384 | 0.91 | UBE2M (0.39) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL25732778 | 0.89 | NPC1 (0.42) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL29851886 | 0.88 | MAPT (0.37) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL23568471 | 0.88 | MAPT (0.37) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL23536221 | 0.88 | MAPT (0.37) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL25726420 | 0.88 | MAPT (0.39) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL23539202 | 0.85 | UBE2M (0.44) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL25726365 | 0.82 | MAPT (0.36) | UBE2MDCUN1D1LMNAPOLBMAPK1 | |
| SCHEMBL29852026 | 0.80 | MAPT (0.39) | UBE2MDCUN1D1LMNAPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052627-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2022-09-13 | — | — | CN | disclosed |