Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294467 | 1.00 | NPC1 (0.45) | NPC1RAB9ACA12LDHATP53 | |
| SCHEMBL23294396 | 0.86 | CA12 (0.47) | CA12LDHATP53CTRCHAO1 | |
| SCHEMBL29852146 | 0.86 | CA12 (0.47) | CA12LDHATP53CTRCHAO1 | |
| SCHEMBL29852112 | 0.84 | CA12 (0.55) | CA12CTRCHAO1 | |
| SCHEMBL23294462 | 0.84 | CA12 (0.55) | CA12CTRCHAO1 | |
| SCHEMBL23294475 | 0.82 | ABL1 (0.37) | CA12KMOHAO1 | |
| SCHEMBL29852148 | 0.82 | ABL1 (0.37) | CA12KMOHAO1 | |
| SCHEMBL23329266 | 0.81 | NPC1 (0.45) | NPC1RAB9ACA12CASP3SENP7 | |
| SCHEMBL23294498 | 0.80 | HAO1 (0.45) | NPC1RAB9ACA12CASP3SENP7 | |
| SCHEMBL29852162 | 0.80 | HAO1 (0.45) | NPC1RAB9ACA12CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-B | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |