Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 12/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23294498 | 1.00 | HAO1 (0.45) | HAO1ABL1ALPLCA9HSP90AA1 | |
| SCHEMBL23294475 | 0.81 | ABL1 (0.37) | HAO1ABL1ALPLHSP90AA1CA12 | |
| SCHEMBL29852148 | 0.81 | ABL1 (0.37) | HAO1ABL1ALPLHSP90AA1CA12 | |
| SCHEMBL29851969 | 0.80 | NPC1 (0.45) | HAO1NPC1CASP3RAB9ASENP7 | |
| SCHEMBL23294467 | 0.80 | NPC1 (0.45) | HAO1NPC1CASP3RAB9ASENP7 | |
| SCHEMBL23294462 | 0.78 | CA12 (0.55) | HAO1ALPLCA12 | |
| SCHEMBL29852112 | 0.78 | CA12 (0.55) | HAO1ALPLCA12 | |
| SCHEMBL23294396 | 0.77 | CA12 (0.47) | HAO1CA12 | |
| SCHEMBL29852146 | 0.77 | CA12 (0.47) | HAO1CA12 | |
| SCHEMBL23294648 | 0.76 | HAO1 (0.56) | HAO1ALPLCA9HSP90AA1PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929676-B | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |