Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 9/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218442 | 1.00 | CFD (0.46) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23219109 | 0.91 | CFD (0.55) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29853190 | 0.91 | CFD (0.55) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29852716 | 0.89 | CFD (0.50) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218093 | 0.89 | CFD (0.50) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218937 | 0.89 | PTGER4 (0.54) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29592367 | 0.89 | PTGER4 (0.54) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23219130 | 0.83 | CFD (0.54) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218897 | 0.83 | CFD (0.54) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29853134 | 0.83 | CFD (0.54) | CFDPLGPLAUF11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |