Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218720 | 1.00 | MAPT (0.45) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL23218500 | 0.92 | MAPT (0.45) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL29853098 | 0.92 | MAPT (0.45) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL23218975 | 0.90 | MAPT (0.42) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL29852463 | 0.89 | MAPT (0.40) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL29852601 | 0.89 | MAPT (0.43) | MAPTPOLBMEN1KMT2ATSHR | |
| SCHEMBL23218045 | 0.89 | MAPT (0.43) | MAPTPOLBMEN1KMT2ATSHR | |
| SCHEMBL23218987 | 0.89 | MAPT (0.40) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL23218949 | 0.89 | TBXAS1 (0.41) | MAPTPOLBMEN1KMT2AGAA | |
| SCHEMBL23219070 | 0.88 | MAPT (0.41) | MAPTPOLBMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |