SCHEMBL2985279

SCHEMBL2985279

O=C(O)[C@H](CO)NCP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 6/20 0.47
MME P08473 6/20 0.47
TGFBR1 P36897 3/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
GGH Q92820 1/20 0.36
ACE P12821 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2987367 1.00 ECE1 (0.47) ECE1MMETGFBR1MEN1KMT2A
SCHEMBL629640 0.84 ECE1 (0.40) ECE1MMETGFBR1MEN1KMT2A
SCHEMBL2992701 0.83 ECE1 (0.41) ECE1MMEMEN1KMT2ACA2
SCHEMBL2992705 0.83 ECE1 (0.41) ECE1MMEMEN1KMT2ACA2
SCHEMBL2988265 0.81 CA2 (0.56) ECE1MMEMEN1KMT2ACA2
SCHEMBL2988262 0.81 CA2 (0.56) ECE1MMEMEN1KMT2ACA2
SCHEMBL3091754 0.81 MME (0.36) ECE1MMETGFBR1MEN1KMT2A
SCHEMBL2988687 0.81 KDM4E (0.45) ECE1MMEMEN1KMT2ACA2
SCHEMBL3091760 0.81 MME (0.36) ECE1MMETGFBR1MEN1KMT2A
SCHEMBL2983953 0.81 ECE1 (0.42) ECE1MMEMEN1KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776844-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2010-08-17 US claimed
US-20090208499-A1 N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use YU RUEY J 2009-08-20 US claimed
US-7572776-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2009-08-11 US claimed
JP-2009526755-A 2009-07-23 JP claimed
CN-101395164-A N- (phosphonoalkyl) -amino acids, derivatives and compositions thereof, and methods of use SCOTT EUGENE J VAN YU RUEY J (US) 2009-03-25 CN claimed
US-20080306025-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2008-12-11 US claimed
EP-1979366-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE Yu, Ruey J. (US) 2008-10-15 EP claimed
US-7429575-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2008-09-30 US claimed
WO-2007082206-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J (US) 2007-07-19 WO claimed
US-20070161543-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2007-07-12 US claimed
CN-104556429-B Water treatment medicament composition and application thereof 中国石油化工股份有限公司 2017-03-22 CN disclosed
CN-101925541-B water treatment method DEQUEST AG 2012-12-19 CN disclosed
CN-102674571-A Method of scale inhibition THERMPHOS TRADING GMBH 2012-09-19 CN disclosed
CN-101500951-B Scale inhibition method THERMPHOS TRADING GMBH 2012-03-14 CN disclosed
CN-101925541-A Water treatment method THERMPHOS TRADING GMBH 2010-12-22 CN disclosed
EP-1979366-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE Yu, Ruey J. (US) 2008-10-15 EP disclosed
US-7429575-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2008-09-30 US disclosed
WO-2008017339-A1 α-AMINO ACID PHOSPHONIC ACID COMPOUNDS, METHOD OF PREPARATION AND USE THEREOF THERMPHOS TRADING GMBH (CH) 2008-02-14 WO disclosed
WO-2007082206-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J (US) 2007-07-19 WO disclosed
US-20070161543-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2007-07-12 US disclosed