Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218748 | 1.00 | MAPT (0.46) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23218949 | 0.92 | TBXAS1 (0.41) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23229139 | 0.89 | GAA (0.58) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23229138 | 0.86 | POLB (0.49) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL32670275 | 0.85 | POLB (0.56) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23117269 | 0.85 | POLB (0.56) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL29853036 | 0.85 | MEN1 (0.47) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23218096 | 0.85 | MEN1 (0.47) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23229127 | 0.84 | MAPT (0.48) | MAPTNPSR1POLBKMT2AMEN1 | |
| SCHEMBL23218873 | 0.82 | MAPT (0.41) | MAPTNPSR1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |