Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 14/20 | 0.54 |
| ▸ | F11 | P03951 | 8/20 | 0.54 |
| ▸ | TPSB2 | P20231 | 7/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218694 | 1.00 | CFD (0.54) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218955 | 0.91 | CFD (0.46) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852605 | 0.91 | CFD (0.46) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23229137 | 0.89 | KDM4E (0.44) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29853120 | 0.89 | CFD (0.57) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218808 | 0.89 | CFD (0.57) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852965 | 0.87 | CFD (0.62) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218758 | 0.87 | CFD (0.62) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218271 | 0.87 | CFD (0.54) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852491 | 0.87 | CFD (0.54) | CFDF11TPSB2KLKB1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |