Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591621 | 1.00 | MAPT (0.38) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL23218123 | 1.00 | MAPT (0.38) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL29853027 | 0.92 | MAPT (0.39) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL23218319 | 0.92 | MAPT (0.39) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL29591201 | 0.92 | MAPT (0.39) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL23218662 | 0.91 | MAPT (0.36) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL29852451 | 0.91 | MAPT (0.36) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL23218321 | 0.90 | TBXAS1 (0.37) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL29593258 | 0.90 | TBXAS1 (0.37) | MAPTTP53THRBTBXAS1PTGDR2 | |
| SCHEMBL23218917 | 0.90 | PTGER4 (0.38) | MAPTTP53THRBTBXAS1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |