Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 18/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 6/20 | 0.46 |
| ▸ | F11 | P03951 | 5/20 | 0.46 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219143 | 1.00 | CFD (0.49) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL23218717 | 0.94 | CFD (0.47) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL29853081 | 0.92 | CFD (0.57) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL23218178 | 0.92 | CFD (0.57) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL29852690 | 0.91 | CFD (0.51) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL23218389 | 0.91 | CFD (0.51) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL29853173 | 0.91 | CFD (0.49) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL23218367 | 0.91 | CFD (0.49) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL23218971 | 0.90 | CFD (0.48) | CFDTPSB2F11PLAUPLG | |
| SCHEMBL28736158 | 0.89 | CFD (0.53) | CFDTPSB2F11PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |