Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218268 | 1.00 | BRD4 (0.35) | BRD4CREBBPTP53CASP1FFAR1 | |
| SCHEMBL23218473 | 0.90 | TP53 (0.35) | BRD4CREBBPTP53CASP1PDCD1 | |
| SCHEMBL29852424 | 0.90 | TP53 (0.35) | BRD4CREBBPTP53CASP1PDCD1 | |
| SCHEMBL23218162 | 0.89 | GRM2 (0.36) | BRD4CREBBPTP53CASP1BCHE | |
| SCHEMBL29852557 | 0.89 | GRM2 (0.36) | BRD4CREBBPTP53CASP1BCHE | |
| SCHEMBL23218237 | 0.89 | TP53 (0.36) | BRD4CREBBPTP53CASP1FFAR1 | |
| SCHEMBL29852677 | 0.89 | TP53 (0.36) | BRD4CREBBPTP53CASP1FFAR1 | |
| SCHEMBL29852642 | 0.86 | CFD (0.42) | CASP1FFAR1CFDMAPTMEN1 | |
| SCHEMBL23218124 | 0.86 | CFD (0.42) | CASP1FFAR1CFDMAPTMEN1 | |
| SCHEMBL21439543 | 0.82 | CFD (0.43) | BRD4CREBBPPDCD1CD274CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |