Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 6/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218443 | 1.00 | CFD (0.43) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218420 | 0.94 | FFAR1 (0.43) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29853023 | 0.94 | FFAR1 (0.43) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29852895 | 0.93 | CFD (0.42) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218490 | 0.93 | CFD (0.42) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23219095 | 0.92 | CFD (0.41) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL29853070 | 0.92 | CFD (0.41) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218448 | 0.91 | CFD (0.41) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218428 | 0.91 | CFD (0.44) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218212 | 0.91 | CFD (0.41) | CFDPLGPLAUF11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |