Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.45 |
| ▸ | ACACA | Q13085 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 14/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218672 | 1.00 | ACACB (0.45) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23218915 | 0.90 | CFD (0.52) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29852739 | 0.90 | CFD (0.52) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29853242 | 0.89 | CFD (0.42) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23218429 | 0.89 | CFD (0.42) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23218562 | 0.88 | CFD (0.44) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218971 | 0.88 | CFD (0.48) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23219143 | 0.84 | CFD (0.49) | CFDPLGPLAUF11KLKB1 | |
| SCHEMBL23218390 | 0.84 | ACACB (0.42) | ACACBACACABRD4 | |
| SCHEMBL29853205 | 0.84 | ACACB (0.42) | ACACBACACABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |