Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29593177 | 1.00 | ALOX15 (0.37) | ALOX15TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL23218334 | 1.00 | ALOX15 (0.37) | ALOX15TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL29852426 | 0.89 | PTGER4 (0.35) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL23219001 | 0.89 | PTGER4 (0.35) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL29591282 | 0.89 | PTGER4 (0.35) | TSHRHSD17B10MEN1KMT2APOLB | |
| SCHEMBL23218319 | 0.87 | MAPT (0.39) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL29591201 | 0.87 | MAPT (0.39) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL29853027 | 0.87 | MAPT (0.39) | MEN1KMT2AMAPTTP53THRB | |
| SCHEMBL23218917 | 0.87 | PTGER4 (0.38) | MEN1KMT2APOLBMAPTTP53 | |
| SCHEMBL29852993 | 0.87 | PTGER4 (0.38) | MEN1KMT2APOLBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |